New generation tissue valves
نویسندگان
چکیده
منابع مشابه
Tissue-engineered heart valves.
Currently-used mechanical and biological heart valve prostheses have several disadvantages. Mechanical prostheses, based on carbon, metallic and polymeric components, require permanent anticoagulation treatment, and their usage often leads to adverse reactions, e.g. thromboembolic complications and endocarditis. Xenogenous and allogenous biological prostheses are associated with immune reaction...
متن کاملNew technique for construction of tissue heart valves.
A new technique for the construction of frame-supported tissue heart valves made of dura mater is presented. Three symmetrical pieces of pentagon-shaped tissue are used instead of the conventional quadrangular shape. A symmetrical trileaflet valve with adequate coaptation and less spherical formation of the cusps is obtained. The design characteristics suggest that regurgitation through the val...
متن کاملTissue engineering of heart valves--human endothelial cell seeding of detergent acellularized porcine valves.
OBJECTIVE Tissue engineering of heart valves represents a new experimental concept to improve current modes of therapy in valvular heart disease. Drawbacks of glutaraldehyde fixed tissue valves or mechanical valves include the short durability or the need for life-long anticoagulation, respectively. Both have in common the inability to grow, which makes valvular heart disease especially problem...
متن کاملA new generation of sodium chloride porogen for tissue engineering.
Porogen leaching is a widely used and simple technique for the creation of porous scaffolds in tissue engineering. Sodium chloride (NaCl) is the most commonly used porogen, but the current grinding and sieving methods generate salt particles with huge size variations and cannot generate porogens in the submicron size range. We have developed a facile method based on the principles of crystalliz...
متن کاملNew antiplatelet agents and prosthetic heart valves.
Sir, Despite advances in prosthetic valve design, patients who undergo valve replacement are at risk of arterial thromboembolism and valve thrombosis. We present four cases where new antiplatelet agents have been used. A 61-year-old man with aortic valve endocarditis underwent early mechanical valve replacement. He developed mitral regurgitation and an aorticright-atrial fistula requiring surgi...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1984
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)38295-9